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PRP and Hair Loss

July 29, 2024

Platelet Rich Plasma for hair loss is the one of the top PRP google searches.  PRP has been used for androgenic hair loss (male and female patterned balding), traction alopecia (due to weaves, braids, wigs, hair extensions, etc), alopecia areata (autoimmune hair loss) and even chemo induced hair loss.

Activated platelets from PRP active growth factors and proteins that signal numerous growth factors, including platelet-derived growth factor, transforming growth factor (TGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor, and interleukin-1.  It is proposed that growth factors released from platelets may act on stem cells in the bulge area of the follicles, thereby stimulating the development of new hair follicles and promoting angiogenesis or blood flow.

There are numerous studies to suggest PRP is a safe and effective alternative to the traditional options of Minoxidil (Rogaine) or Finasteride (Propecia) which have potential side effects.  PRP can also be used in conjunction to hair transplantation.  While a consensus still needs to be reached in the research world of PRP for hair loss, most of the studies show a need for several treatments–3 treatments roughly 1 month apart are recommended.  Maintenance treatment may also be required.  Results are very individualized.  The procedure requires approximately 1 hour.

PRP for hair loss is an off label indication, so this is not covered by insurance.

References:

Indian J Plast Surg. 2015 Jan-Apr; 48(1): 57–59, Role of Platelet-rich plasma in chronic alopecia areata:  our centre experience.
Trink A et al. A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet rich plasma on alopecia. British Journal of Dermatology 2013; 169: 690-94

Int J Womens Dermatol. 2019 Feb; 5(1): 46–51.  Platelet-rich plasma for androgenetic alopecia:  A review of the literature and proposed treatment protocol.

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